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Melanotan-1 Dosing Protocol Comparison

Loading Phase 0.25–1mg Daily 10–14 days 5–10 min within 1 hour post-injection Visible pigmentation increase; receptor saturation Maintenance Phase 0.25–0.5mg 2–3x weekly Ongoing (12–16 weeks typical) 5 min within 1 hour post-injection Sustained pigmentation; m

This comparison does not assign a generated winner or score.

  • Loading Phase
  • 0.25–1mg
  • Daily
  • 10–14 days
  • 5–10 min within 1 hour post-injection
  • Visible pigmentation increase; receptor saturation
  • Maintenance Phase
  • 0.25–0.5mg
  • 2–3x weekly
  • Ongoing (12–16 weeks typical)
  • 5 min within 1 hour post-injection
  • Sustained pigmentation; minimal additional darkening
  • Tolerance Test
  • 0.25mg
  • Once
  • Day 1–3
  • Optional (monitor for nausea before UV)
  • Assess GI tolerance before dose escalation
  • High-Response Protocol
  • 0.5–0.75mg
  • 10 days
  • 8–10 min UVB at 0.75 MED
  • Rapid pigmentation for Type I–II skin; higher nausea risk
  • Minimal Protocol
  • 3x weekly
  • 14–21 days
  • 5 min post-injection
  • Gradual pigmentation; lowest side effect profile
  • Professional Assessment
  • Start low (0.25mg), titrate based on nausea tolerance and pigmentation response. UV exposure is non-negotiable. Without it, melanocyte activation doesn't occur.
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