Source comparison
Melanotan-1 Dosing: Protocol Comparison
Loading (Fair Skin, Fitzpatrick I–II) 0.25–0.5mg Daily or alternate-day 14–20 days 30–50% increase from baseline Lower doses reduce nausea and flushing Loading (Moderate Skin, Fitzpatrick III–IV) 0.5–1.0mg 10–14 days 50–70% increase from baseline Higher baseli
This comparison does not assign a generated winner or score.
- Loading (Fair Skin, Fitzpatrick I–II)
- 0.25–0.5mg
- Daily or alternate-day
- 14–20 days
- 30–50% increase from baseline
- Lower doses reduce nausea and flushing
- Loading (Moderate Skin, Fitzpatrick III–IV)
- 0.5–1.0mg
- 10–14 days
- 50–70% increase from baseline
- Higher baseline melanin allows faster loading
- Maintenance (All Skin Types)
- 2–3 times weekly
- Ongoing
- Sustained at peak achieved during loading
- Maintains tyrosinase activity without daily stimulation
- Rapid Loading (Research Setting)
- 1.0mg
- Daily
- 7–10 days
- 40–60% increase, higher adverse event rate
- Used in controlled studies with medical oversight