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Melanotan-1 Dosing: Research Protocol Comparison

Photoprotection (Type I–II) 0.5–0.8mg 7–10 days 7–10mg over 14 days 50% reduction in MED; visible tan in 85% of subjects Nausea 22%, flushing 18% Gold standard for fair-skinned photoprotection research. Balances efficacy with tolerability Accelerated Tanning (

This comparison does not assign a generated winner or score.

  • Photoprotection (Type I–II)
  • 0.5–0.8mg
  • 7–10 days
  • 7–10mg over 14 days
  • 50% reduction in MED; visible tan in 85% of subjects
  • Nausea 22%, flushing 18%
  • Gold standard for fair-skinned photoprotection research. Balances efficacy with tolerability
  • Accelerated Tanning (Type I–II)
  • 0.8–1mg
  • 5–7 days
  • 10–12mg over 12 days
  • Visible tan in 90% by day 8; 60% MED reduction
  • Nausea 35%, flushing 28%
  • Higher efficacy but increased side effects. Reserve for subjects with prior melanocortin exposure
  • Maintenance (Type III–IV)
  • 0.25–0.5mg
  • 3–5 days
  • 4–6mg over 14 days
  • Sustained baseline pigmentation; 30% MED reduction
  • Nausea 12%, flushing 8%
  • Lower doses sufficient in darker phototypes. Avoid overstimulation
  • Conservative Titration (Type I)
  • 10–14 days
  • 5–7mg over 14 days
  • Gradual tan onset; 40% MED reduction
  • Nausea 10%, flushing 6%
  • Minimises adverse events at cost of slower onset. Ideal for first-time protocols
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