Melanotan-1 Dosing: Research Protocol Comparison
Photoprotection (Type I–II) 0.5–0.8mg 7–10 days 7–10mg over 14 days 50% reduction in MED; visible tan in 85% of subjects Nausea 22%, flushing 18% Gold standard for fair-skinned photoprotection research. Balances efficacy with tolerability Accelerated Tanning (
This comparison does not assign a generated winner or score.
- Photoprotection (Type I–II)
- 0.5–0.8mg
- 7–10 days
- 7–10mg over 14 days
- 50% reduction in MED; visible tan in 85% of subjects
- Nausea 22%, flushing 18%
- Gold standard for fair-skinned photoprotection research. Balances efficacy with tolerability
- Accelerated Tanning (Type I–II)
- 0.8–1mg
- 5–7 days
- 10–12mg over 12 days
- Visible tan in 90% by day 8; 60% MED reduction
- Nausea 35%, flushing 28%
- Higher efficacy but increased side effects. Reserve for subjects with prior melanocortin exposure
- Maintenance (Type III–IV)
- 0.25–0.5mg
- 3–5 days
- 4–6mg over 14 days
- Sustained baseline pigmentation; 30% MED reduction
- Nausea 12%, flushing 8%
- Lower doses sufficient in darker phototypes. Avoid overstimulation
- Conservative Titration (Type I)
- 10–14 days
- 5–7mg over 14 days
- Gradual tan onset; 40% MED reduction
- Nausea 10%, flushing 6%
- Minimises adverse events at cost of slower onset. Ideal for first-time protocols