Source comparison
Melanotan-1 Response Timeline Comparison
Fitzpatrick I-II (Very Fair) 7-10 days 5-6 weeks Controlled UVB 3×/week essential Golden to light brown; may appear uneven initially Longest priming phase; requires strict photoprotection protocol to avoid patchy results Fitzpatrick III-IV (Medium-Olive) 5-7 d
This comparison does not assign a generated winner or score.
- Fitzpatrick I-II (Very Fair)
- 7-10 days
- 5-6 weeks
- Controlled UVB 3×/week essential
- Golden to light brown; may appear uneven initially
- Longest priming phase; requires strict photoprotection protocol to avoid patchy results
- Fitzpatrick III-IV (Medium-Olive)
- 5-7 days
- 3-4 weeks
- Moderate UVB 2-3×/week recommended
- Deep brown; uniform distribution
- Ideal response cohort; most dramatic cosmetic contrast; shortest time to plateau
- Fitzpatrick V-VI (Dark Brown-Black)
- Minimal visible change
- N/A (photoprotection primary endpoint)
- UV not required for melanin synthesis
- Subtle darkening; eumelanin dominant
- Peptide increases photoprotection measurably but cosmetic change negligible; research use targets erythema reduction
- MC1R Loss-of-Function (Red Hair Gene)
- 8-12 days
- 5-7 weeks
- UVB required but risk of burn elevated
- Golden-red to copper; lower eumelanin ratio
- Blunted eumelanin response; pheomelanin-dominant pigmentation; higher nausea incidence