Source comparison
MK-677 Blood Work Labs: Detailed Comparison
IGF-1 Establishes starting point Confirms response to dosing Tracks sustained elevation Confirms return to baseline Most users see 50–90% increase; 100% may warrant dose reduction Fasting Glucose Normal <100 mg/dL Should remain <100
This comparison does not assign a generated winner or score.
- IGF-1
- Establishes starting point
- Confirms response to dosing
- Tracks sustained elevation
- Confirms return to baseline
- Most users see 50–90% increase; <30% suggests underdosing, >100% may warrant dose reduction
- Fasting Glucose
- Normal <100 mg/dL
- Should remain <100 mg/dL
- Trend matters. Rising values signal insulin resistance
- Should normalize to baseline
- Elevations of 6–15 mg/dL are common; persistent ≥100 mg/dL requires intervention
- HbA1c
- Normal <5.7%
- Minimal change expected
- Detects progressive glucose dysregulation
- Should return to baseline
- Increases >0.3% over 12 weeks indicate metabolic stress
- Fasting Insulin
- Normal 2–25 µIU/mL
- Pair with glucose to calculate HOMA-IR
- Values >15 µIU/mL suggest insulin resistance
- Elevated insulin + elevated glucose = developing insulin resistance
- Prolactin
- Men <18 ng/mL, women <25 ng/mL
- Catch early spikes (15–25% of users)
- Sustained elevation warrants dose adjustment
- Should drop to baseline
- Transient spikes are common; persistent >30 ng/mL requires investigation
- Cortisol (AM)
- Normal 10–20 µg/dL
- May rise 10–15% in some users
- Usually resolves with continued use
- Mild elevation is benign; >25 µg/dL suggests HPA axis dysregulation
- Thyroid Panel (TSH, fT3, fT4)
- Establishes euthyroid status
- Rarely changes acutely
- Detect suppressed fT3 if symptoms arise
- Confirms recovery
- Hypothyroid symptoms on-cycle may reflect TSH-IGF-1 interaction, not true hypothyroidism