Source comparison
MK-677 Diabetes Risk Blood Sugar Monitoring — Comparison Table
Fasting Glucose (Fingerstick or Lab) Weekly for first 4 weeks, then biweekly Current glucose level after 8–12 hour fast ≥100 mg/dL on two consecutive measurements Most accessible baseline metric. Catches early drift before HbA1c rises HbA1c (Lab Test) Baseline
This comparison does not assign a generated winner or score.
- Fasting Glucose (Fingerstick or Lab)
- Weekly for first 4 weeks, then biweekly
- Current glucose level after 8–12 hour fast
- ≥100 mg/dL on two consecutive measurements
- Most accessible baseline metric. Catches early drift before HbA1c rises
- HbA1c (Lab Test)
- Baseline, then every 8–12 weeks
- Average glucose over preceding 90–120 days
- Increase of ≥0.3 percentage points from baseline
- Best marker for cumulative glucose exposure. Lags behind acute changes
- Fasting Insulin (Lab Test)
- Baseline, then at week 8 and week 16
- Pancreatic compensatory response to insulin resistance
- ≥10 µIU/mL (suggests hyperinsulinemia)
- Most sensitive early marker. Rises before fasting glucose becomes abnormal
- Continuous Glucose Monitor (CGM)
- Worn continuously throughout research cycle
- Real-time glucose trends, postprandial peaks, nocturnal patterns
- Postprandial glucose ≥140 mg/dL or time-in-range <70%
- Reveals glucose variability that fasting measurements miss. Ideal for protocol optimisation
- HOMA-IR Calculation
- Baseline, then every 8 weeks
- Insulin resistance index derived from fasting glucose and insulin
- ≥2.5 (indicates insulin resistance)
- Integrates both glucose and insulin into a single metric. Most comprehensive assessment