Source comparison
MK-677 for Bodybuilders: Performance Comparison
MK-677 Ghrelin receptor agonist (oral GH secretagogue) 20–25mg daily Strength gains visible 4–6 weeks; IGF-1 elevation sustained 24 hours Water retention, increased appetite, transient insulin resistance Best for athletes prioritising recovery and lean mass wi
This comparison does not assign a generated winner or score.
- MK-677
- Ghrelin receptor agonist (oral GH secretagogue)
- 20–25mg daily
- Strength gains visible 4–6 weeks; IGF-1 elevation sustained 24 hours
- Water retention, increased appetite, transient insulin resistance
- Best for athletes prioritising recovery and lean mass without injection protocols. Manageable sides with proper electrolyte control
- Exogenous GH (Somatropin)
- Direct hormone replacement (subcutaneous injection)
- 2–4 IU daily
- Immediate IGF-1 spike; muscle hardness within 2–3 weeks
- Significant water retention, carpal tunnel, potential for acromegaly at high doses
- Superior anabolic potency but requires daily injections, refrigerated storage, and costs 8–10× more than MK-677
- SARMs (e.g., LGD-4033)
- Selective androgen receptor modulation (oral)
- 5–10mg daily
- Strength and mass gains within 3–4 weeks
- Testosterone suppression (requires PCT), potential liver stress
- Directly builds muscle via androgen pathways; stacks well with MK-677 for dual-mechanism anabolism
- Creatine Monohydrate
- Increases phosphocreatine stores for ATP regeneration
- 5g daily
- Strength boost within 1 week; 2–4 lb water weight gain
- Minimal (mild GI upset in some users)
- Foundational supplement. Cheaper and safer than any other option but limited anabolic ceiling compared to MK-677
- Peptide Stack (GHRP-2 + Mod GRF)
- Dual-action GH release (subcutaneous injection)
- 100mcg each 2–3× daily
- Comparable IGF-1 elevation to MK-677 but requires multiple daily doses
- Injection site irritation, cortisol spike with GHRP-6 variants
- More precise GH pulsing than MK-677 but logistically demanding. Best for advanced users