Source comparison
MK-677 Research Protocols: Comparison of Storage and Handling Methods
Lyophilised powder (unopened) −20°C 12–24 months Minimal if sealed No (powder form stable) Optimal for long-term inventory. Degradation negligible under proper freezer storage Reconstituted with bacteriostatic water 2–8°C refrigerated 28 days Moderate (multi-d
This comparison does not assign a generated winner or score.
- Lyophilised powder (unopened)
- −20°C
- 12–24 months
- Minimal if sealed
- No (powder form stable)
- Optimal for long-term inventory. Degradation negligible under proper freezer storage
- Reconstituted with bacteriostatic water
- 2–8°C refrigerated
- 28 days
- Moderate (multi-dose access)
- Yes (amber vial or foil wrap)
- Standard for multi-week protocols. Benzyl alcohol prevents bacterial growth but not photodegradation
- Reconstituted with sterile water
- 7 days maximum
- High (no preservative)
- Yes
- Single-use or short-term only. Sterile water offers no contamination barrier after initial draw
- Frozen reconstituted aliquots
- Not recommended
- Low (single-use thaw)
- Yes (if clear vials used)
- Last resort only. Freeze-thaw cycles rupture peptide structure; potency loss 15–30%
- Ambient temperature (reconstituted)
- 20–25°C
- Hours to 2 days
- Very high
- Critical
- Avoid entirely. Rapid degradation + bacterial proliferation in bacteriostatic water above 10°C
- Light-exposed refrigerated storage
- 2–8°C
- 14 days effective
- Moderate
- Not provided (failure mode)
- Photodegradation reduces potency 10–25% within 72 hours under fluorescent lab lighting