Source comparison
MK-677 Results After 1 Month: Research vs Marketing Comparison
Serum IGF-1 Elevation 'Massive GH boost' 18–25% mean increase from baseline (JCEM 2019) Significant but modest. Individual response varies 10–40% based on age and baseline Lean Body Mass Gain '5–10 lbs of muscle in 4 weeks' 0.8 kg mean increase, non-significan
This comparison does not assign a generated winner or score.
- Serum IGF-1 Elevation
- 'Massive GH boost'
- 18–25% mean increase from baseline (JCEM 2019)
- Significant but modest. Individual response varies 10–40% based on age and baseline
- Lean Body Mass Gain
- '5–10 lbs of muscle in 4 weeks'
- 0.8 kg mean increase, non-significant vs placebo (JCEM 2008)
- Not detectable at 30 days. Hypertrophy requires 8+ weeks sustained dosing
- Fat Loss
- 'Shreds body fat rapidly'
- No significant reduction in fat mass at 4 weeks (multiple trials)
- GH does stimulate lipolysis, but measurable fat loss requires 12+ weeks and caloric deficit
- Sleep Quality
- 'Improves rest and recovery'
- 50% increase in REM duration, 20% increase in slow-wave sleep (Psychoneuroendocrinology)
- Objective and significant. One of the most consistent first-month effects
- Strength Increases
- 'Rapid strength gains'
- No performance benefit detected in 4-week trials
- Strength adaptations lag behind IGF-1 elevation. Neural and hypertrophic gains appear after 8–12 weeks
- Water Retention
- Rarely mentioned
- 2–4 lbs intracellular fluid gain in most users
- Common and benign. Mistaken for muscle gain or fat gain depending on user expectation