Source comparison
MK-677 Stability Comparison
Lyophilised at −20°C 24–36 months 95–98% Ideal long-term storage; no degradation pathways active Gold standard. Use this until ready to reconstitute Reconstituted at 2–4°C 28 days 90–95% Standard refrigeration; bacteriostatic water required Optimal. This is th
This comparison does not assign a generated winner or score.
- Lyophilised at −20°C
- 24–36 months
- 95–98%
- Ideal long-term storage; no degradation pathways active
- Gold standard. Use this until ready to reconstitute
- Reconstituted at 2–4°C
- 28 days
- 90–95%
- Standard refrigeration; bacteriostatic water required
- Optimal. This is the target storage condition
- Reconstituted at 8°C
- 21 days
- 85–90%
- Upper refrigeration limit; degradation accelerates
- Acceptable short-term but tighten cold chain
- Reconstituted at 15°C
- 7 days
- 70–80%
- Cool room temp; hydrolysis rates triple vs refrigeration
- Unacceptable. Potency loss too rapid
- Reconstituted at 25°C
- 3–5 days
- 50–60%
- Room temperature; complete degradation within two weeks
- Research-grade compound becomes unreliable
- Frozen reconstituted solution
- Not recommended
- Unknown; likely 40–70%
- Ice crystal formation damages peptide structure
- Freezing reconstituted peptides destroys them
- This table shows the hard relationship between storage temperature and MK-677 stability once reconstituted. The 2–4°C range isn't a recommendation. It's the only condition under which long is MK-677 stable once reconstituted extends to the full 28-day window. Anything warmer accelerates degradation exponentially, and freezing reconstituted solutions causes physical damage from ice crystal expansion that denatures the compound.