Source comparison
MK677 Same as MK-677: Comparison of Research Formulations
Ibutamoren Mesylate (Salt Form) 98–99.5% HPLC 60–65% 24 months at −20°C 10–25mg daily Industry-standard form. Highest solubility and batch consistency for controlled studies Free-Base Ibutamoren 95–98% HPLC 55–60% 18 months at −20°C Less common. Lower aqueous
This comparison does not assign a generated winner or score.
- Ibutamoren Mesylate (Salt Form)
- 98–99.5% HPLC
- 60–65%
- 24 months at −20°C
- 10–25mg daily
- Industry-standard form. Highest solubility and batch consistency for controlled studies
- Free-Base Ibutamoren
- 95–98% HPLC
- 55–60%
- 18 months at −20°C
- Less common. Lower aqueous solubility complicates dosing precision in aqueous protocols
- Pre-Mixed Suspension (PEG/DMSO)
- Variable (85–95%)
- Not applicable (already dissolved)
- 6 months refrigerated
- Variable
- Convenient but stability concerns. Degrades faster than lyophilised powder
- Research-Grade Powder (Third-Party)
- 90–98% HPLC
- 12–18 months at −20°C
- Quality depends heavily on supplier. Certificate of analysis (CoA) verification essential
- MK677 and MK-677 appear in all four formulation types above with identical chemical structure. The designation does not change the molecule. The mesylate salt form dominates research applications because it dissolves readily in bacteriostatic water and maintains consistent potency across freeze-thaw cycles, critical for multi-dose reconstitution protocols. Free-base formulations require DMSO or ethanol as a carrier solvent, which introduces variables that complicate standardised dosing.
- Supplier variability represents the single largest quality risk when sourcing ibutamoren. Some catalogues list MK677 at 99% purity without providing third-party verification. Claims that should trigger immediate CoA requests. Legitimate research-grade suppliers provide batch-specific HPLC and mass spectrometry reports confirming molecular weight, purity percentage, and absence of contaminating peptides or synthesis byproducts. Without these documents, there is no way to verify that MK677 same as MK-677 in both name and actual compound identity.