Source comparison
MOTS-C COA: Quality Metrics Comparison
HPLC Purity Percentage of target peptide vs total peptide content ≥98.0% Synthesis byproducts, incomplete sequences, residual coupling agents Primary indicator of product quality. Purity <97% suggests poor synthesis control or inadequate purification Mass Spec
This comparison does not assign a generated winner or score.
- HPLC Purity
- Percentage of target peptide vs total peptide content
- ≥98.0%
- Synthesis byproducts, incomplete sequences, residual coupling agents
- Primary indicator of product quality. Purity <97% suggests poor synthesis control or inadequate purification
- Mass Spectrometry
- Molecular weight confirmation
- 1599.85 Da ±1.0 Da
- Wrong sequence, amino acid substitutions, or degradation
- Independent verification that the HPLC main peak is actually MOTS-C. Critical for research reproducibility
- Endotoxin Testing (LAL)
- Bacterial endotoxin contamination
- <1.0 EU/mg
- Contamination during synthesis or lyophilisation
- Essential for any in vivo application. High endotoxin triggers immune responses that confound experimental results
- Peptide Content
- Total peptide as percentage of net weight
- 70–85% (rest is counterions and residual water)
- Incorrect fill weight or excessive hygroscopic water absorption
- Low peptide content means you're dosing less active compound than calculated. Affects concentration accuracy
- Appearance
- Visual inspection of lyophilised powder
- White to off-white powder, no discoloration
- Oxidation, degradation, or thermal damage during lyophilisation
- Yellowing or clumping visible before opening suggests storage failure or manufacturing defects