Source comparison
MOTS-c for Cyclists: Performance Comparison
VO2 Max Improvement (8 weeks) +8–12% +4–6% Increased mitochondrial density via PGC-1α upregulation Meaningful aerobic capacity gain. MOTS-c amplifies training stimulus Lactate Threshold Power (watts) +15–20W +8–10W Enhanced fat oxidation spares glycogen, delay
This comparison does not assign a generated winner or score.
- VO2 Max Improvement (8 weeks)
- +8–12%
- +4–6%
- Increased mitochondrial density via PGC-1α upregulation
- Meaningful aerobic capacity gain. MOTS-c amplifies training stimulus
- Lactate Threshold Power (watts)
- +15–20W
- +8–10W
- Enhanced fat oxidation spares glycogen, delays lactate accumulation
- Threshold gains translate directly to sustained climbing and TT performance
- Recovery Time (post-threshold session)
- 36–42 hours
- 48–60 hours
- Reduced oxidative stress and accelerated mitochondrial repair
- Faster recovery enables higher weekly training load without overreaching
- Time-to-Exhaustion at Threshold
- +18–25%
- Improved substrate efficiency and ATP production per O2 consumed
- Endurance at race pace improves. Critical for breakaway efforts
- Regulatory Status (WADA)
- Prohibited (S0, S4)
- N/A
- AMPK activation = metabolic modulator
- Competitive cyclists face sanctions risk. Non-tested athletes unrestricted