Source comparison
MOTS-c for Muscle Recovery Research Evidence: Key Study Comparisons
Lee et al., Cell Metabolism 2015 Human (insulin-resistant adults) 5mg daily SC 14 days Improved glucose tolerance, reduced HbA1c by 0.3% Metabolic efficiency supports faster substrate recovery Kumamoto Univ., Nature Comm. 2016 Mice (middle-aged) 5mg/kg IP 21 d
This comparison does not assign a generated winner or score.
- Lee et al., Cell Metabolism 2015
- Human (insulin-resistant adults)
- 5mg daily SC
- 14 days
- Improved glucose tolerance, reduced HbA1c by 0.3%
- Metabolic efficiency supports faster substrate recovery
- Kumamoto Univ., Nature Comm. 2016
- Mice (middle-aged)
- 5mg/kg IP
- 21 days
- 30–40% endurance improvement, increased mitochondrial biogenesis
- Endurance gains suggest improved energy production capacity
- Reynolds et al., Aging 2021
- Human (overweight adults)
- 15mg SC
- Fasting glucose −8mg/dL, improved insulin sensitivity
- Lower baseline inflammation may reduce systemic recovery time
- FASEB 2020
- Rats (forced swim test)
- 10mg/kg IP
- Single dose
- Lactate clearance 40% faster than control
- Direct marker of metabolic recovery speed