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MOTS-c Lyophilized Powder: Storage Comparison

Unreconstituted (lyophilized powder) 12–24 months −20°C to −15°C Store in original sealed vial; avoid freeze-thaw cycles; protect from light and moisture Optimal for long-term storage. Peptide remains stable in solid state with <2% degradation annually Reconst

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  • Unreconstituted (lyophilized powder)
  • 12–24 months
  • −20°C to −15°C
  • Store in original sealed vial; avoid freeze-thaw cycles; protect from light and moisture
  • Optimal for long-term storage. Peptide remains stable in solid state with <2% degradation annually
  • Reconstituted with bacteriostatic water
  • 28 days maximum
  • 2–8°C (refrigerated)
  • Must remain refrigerated at all times; use within 4 weeks; protect from light; do not freeze
  • Standard working solution. Bioactivity maintained for 28 days if temperature never exceeds 8°C
  • Reconstituted with sterile water (non-bacteriostatic)
  • 7 days maximum
  • Higher contamination risk; use within 1 week; refrigeration mandatory; single-use vials preferred
  • Not recommended for multi-dose protocols. Bacterial growth risk increases significantly after 7 days
  • Temperature excursion (>10°C for >2 hours)
  • Immediate degradation
  • Above 10°C
  • Irreversible protein denaturation occurs; solution may appear clear but bioactivity is compromised
  • Discard immediately. No recovery method exists; appearance does not indicate potency
  • Frozen reconstituted solution
  • Permanent loss of activity
  • Below 0°C
  • Ice crystal formation disrupts hydrogen bonding and tertiary structure
  • Never freeze reconstituted peptides. Lyophilization cannot be reversed at home
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