MOTS-C Protocol: Dosing Comparison for Endurance Athletes
Standard Research Protocol 5mg 3x/week 15mg 3–4 weeks General aerobic capacity improvement, first-time users Gold standard for documented efficacy. Start here High-Volume Protocol 7.5mg 22.5mg Athletes training 15+ hours/week, multi-day stage races Marginal ga
This comparison does not assign a generated winner or score.
- Standard Research Protocol
- 5mg
- 3x/week
- 15mg
- 3–4 weeks
- General aerobic capacity improvement, first-time users
- Gold standard for documented efficacy. Start here
- High-Volume Protocol
- 7.5mg
- 22.5mg
- Athletes training 15+ hours/week, multi-day stage races
- Marginal gains over standard dose. Reserve for specific race blocks
- Maintenance Protocol
- 2x/week
- 10mg
- 4–6 weeks
- Off-season base building, injury recovery periods
- Sufficient to maintain mitochondrial signalling without peak racing demands
- Intensive Protocol
- 30mg
- 2–3 weeks
- Elite competitors in final preparation phase
- No evidence of superior outcomes vs 5mg. Higher dose = higher cost, not higher performance