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MOTS-C Protocol: Dosing Comparison for Endurance Athletes

Standard Research Protocol 5mg 3x/week 15mg 3–4 weeks General aerobic capacity improvement, first-time users Gold standard for documented efficacy. Start here High-Volume Protocol 7.5mg 22.5mg Athletes training 15+ hours/week, multi-day stage races Marginal ga

This comparison does not assign a generated winner or score.

  • Standard Research Protocol
  • 5mg
  • 3x/week
  • 15mg
  • 3–4 weeks
  • General aerobic capacity improvement, first-time users
  • Gold standard for documented efficacy. Start here
  • High-Volume Protocol
  • 7.5mg
  • 22.5mg
  • Athletes training 15+ hours/week, multi-day stage races
  • Marginal gains over standard dose. Reserve for specific race blocks
  • Maintenance Protocol
  • 2x/week
  • 10mg
  • 4–6 weeks
  • Off-season base building, injury recovery periods
  • Sufficient to maintain mitochondrial signalling without peak racing demands
  • Intensive Protocol
  • 30mg
  • 2–3 weeks
  • Elite competitors in final preparation phase
  • No evidence of superior outcomes vs 5mg. Higher dose = higher cost, not higher performance
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