Source comparison
MOTS-c Results After 1 Month: Comparison
Fasting Glucose No change to 2–4 mg/dL reduction 3–7 mg/dL reduction 8–15 mg/dL reduction in insulin-resistant populations Earliest detectable metabolic shift. Reliable signal if baseline glucose >95 mg/dL Fasting Insulin Minimal change 8–12% reduction 18–25%
This comparison does not assign a generated winner or score.
- Fasting Glucose
- No change to 2–4 mg/dL reduction
- 3–7 mg/dL reduction
- 8–15 mg/dL reduction in insulin-resistant populations
- Earliest detectable metabolic shift. Reliable signal if baseline glucose >95 mg/dL
- Fasting Insulin
- Minimal change
- 8–12% reduction
- 18–25% reduction
- Leading indicator of improved insulin sensitivity. More sensitive than glucose alone
- Subjective Energy
- Variable. 20–30% report mild improvement
- 40–60% report noticeable improvement
- Sustained improvement in 65–75%
- Heavily influenced by sleep quality, stress, and baseline mitochondrial function
- Fat Loss
- Not measurable
- 0.5–1.5 lbs (overlaps with dietary noise)
- 3–6 lbs in sustained deficit with training
- MOTS-c accelerates fat oxidation. Doesn't create the deficit required for loss
- Endurance Performance
- No measurable change
- 3–7% improvement in sustained aerobic output
- 10–15% improvement vs baseline
- Gains depend on training stimulus. Sedentary users see minimal performance change
- Inflammatory Markers (hs-CRP)
- Minimal
- 10–20% reduction if baseline elevated
- 20–35% reduction
- Anti-inflammatory effects strengthen with duration. Early changes inconsistent