Source comparison
MOTS-c Results After 2 Weeks: Comparison
Fasting Glucose 95 mg/dL 88–92 mg/dL Improved GLUT4 expression and insulin-independent glucose uptake in muscle tissue Modest improvement. Meaningful for insulin-resistant individuals, negligible for metabolically healthy users Subjective Energy (1–10 scale) 5
This comparison does not assign a generated winner or score.
- Fasting Glucose
- 95 mg/dL
- 88–92 mg/dL
- Improved GLUT4 expression and insulin-independent glucose uptake in muscle tissue
- Modest improvement. Meaningful for insulin-resistant individuals, negligible for metabolically healthy users
- Subjective Energy (1–10 scale)
- 5/10
- 6.5–7/10
- Increased mitochondrial density (PGC-1α activation) and ATP production capacity
- Most consistent early marker. Correlates with compliance
- Body Weight
- Baseline
- −0.5 to −1.5 lbs
- Water weight fluctuation, not fat loss. AMPK doesn't drive caloric deficit on its own
- Essentially unchanged. Genuine fat loss requires 4+ weeks
- VO2 Max (mL/kg/min)
- No change
- Cardiovascular adaptations lag mitochondrial changes by 3–4 weeks
- Too early to measure. Aerobic capacity improvements appear after week 4
- Mitochondrial Biogenesis Markers (PGC-1α)
- +20–35% (rodent models)
- Direct AMPK activation of transcription factors regulating mitochondrial replication
- Real change at cellular level. Not yet reflected in performance metrics