Source comparison
MOTS-C Storage: Duration and Stability Comparison
Lyophilised powder at −20°C with desiccant 12–18 months Moisture reabsorption, temperature cycling in frost-free freezers Gold standard for long-term storage. Requires strict moisture control and manual-defrost freezer for best results Lyophilised powder at 2–
This comparison does not assign a generated winner or score.
- Lyophilised powder at −20°C with desiccant
- 12–18 months
- Moisture reabsorption, temperature cycling in frost-free freezers
- Gold standard for long-term storage. Requires strict moisture control and manual-defrost freezer for best results
- Lyophilised powder at 2–8°C
- 3–6 months
- Accelerated hydrolysis at above-freezing temps, moisture absorption
- Acceptable for short-term storage only. Not recommended beyond six months due to progressive hydrolysis
- Reconstituted in bacteriostatic water at 2–8°C
- 28 days
- Aggregation, oxidation, enzymatic degradation, repeated temperature exposure
- Standard protocol for active use. Mark reconstitution date on vial and discard after 28 days regardless of appearance
- Reconstituted at room temperature (20–25°C)
- 6–12 hours
- Rapid aggregation, bacterial contamination risk, oxidation
- Emergency-only scenario. Refrigerate immediately upon return to avoid total loss
- Freeze-thaw cycles (any form)
- Immediate degradation with each cycle
- Ice crystal formation, structural disruption
- Never refreeze reconstituted solution. Cumulative activity loss of 10–15% per cycle