Source comparison
Peptide Mechanism and Dosing Comparison
| Peptide | Receptor Target | Mechanism | Typical Dose | Frequency | Half-Life | Professional Assessment ||—|—|—|—|—|—|| CJC-1295 (with DAC) | GHRH receptors (pituitary) | Sustained GH release via GHRH pathway activation | 1–2mg per week | 2× weekly | 6–8 days
This comparison does not assign a generated winner or score.
- | Peptide | Receptor Target | Mechanism | Typical Dose | Frequency | Half-Life | Professional Assessment ||—|—|—|—|—|—|| CJC-1295 (with DAC) | GHRH receptors (pituitary) | Sustained GH release via GHRH pathway activation | 1–2mg per week | 2× weekly | 6–8 days | Best for sustained IGF-1 elevation; reduces injection frequency but limits timing control around training || Ipamorelin | Ghrelin receptors (GHS-R1a) | Pulsatile GH release; minimal cortisol/prolactin elevation | 200–300mcg | 2–3× daily | 2 hours | Ideal for precise timing (pre-training, pre-sleep); pairs well with GHRH analogs for synergistic effect || MK-677 (Ibutamoren) | Ghrelin mimetic (oral) | Oral ghrelin receptor agonist; elevates appetite and IGF-1 | 25mg | 1× daily | 24 hours | Convenient but increases appetite significantly; less precise timing; suitable for bulking phases || Hexarelin | Ghrelin and CD36 receptors | Strongest GH pulse of GHRPs; desensitizes quickly | 100–200mcg | 1–2× daily | 1–2 hours | Potent but n