Source comparison
Peptides for Athletic Performance: Category Comparison
Growth Hormone Secretagogues (GHRP-2, Ipamorelin, MK-677) Bind to ghrelin receptors in pituitary gland, triggering endogenous GH release and downstream IGF-1 synthesis 100–300mcg 1–3× daily, pre-sleep or pre-workout GH spike within 30 minutes; tissue effects a
This comparison does not assign a generated winner or score.
- Growth Hormone Secretagogues (GHRP-2, Ipamorelin, MK-677)
- Bind to ghrelin receptors in pituitary gland, triggering endogenous GH release and downstream IGF-1 synthesis
- 100–300mcg 1–3× daily, pre-sleep or pre-workout
- GH spike within 30 minutes; tissue effects accumulate over 4–8 weeks
- Most clinically validated category with robust human trial data. Effective for lean mass gain and recovery when dosed correctly
- Tissue Repair Peptides (TB-500, BPC-157)
- Promote cell migration, angiogenesis, and collagen synthesis directly at injury sites via VEGF and growth factor modulation
- TB-500: 2–2.5mg 2× weekly; BPC-157: 250–500mcg daily for 4–6 weeks
- Gradual improvement over 2–4 weeks as tissue remodeling occurs
- Strongest evidence for localized tendon and ligament injuries. Not a quick fix but accelerates healing beyond passive recovery
- Mitochondrial Peptides (MOTS-c, Humanin)
- Activate AMPK and protect mitochondrial function, improving fat oxidation and reducing oxidative stress
- MOTS-c: 5–10mg 2–3× weekly; Humanin: protocols still emerging
- Metabolic shifts within days; endurance gains accumulate over weeks
- Cutting-edge research area with promising mechanisms but limited long-term human data. Best suited for endurance athletes
- Immune Modulation Peptides (Thymalin)
- Support thymus function and T-cell production, critical for maintaining immune competence during heavy training
- Variable based on research design
- Immune markers improve over 2–3 weeks
- Useful for athletes experiencing recurrent illness during high-volume phases. Thymalin represents research-grade options