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Peptides for Injury Recovery: Mechanisms Comparison

BPC-157 VEGF upregulation, angiogenesis promotion, fibroblast activation Tendons, ligaments, muscle, GI mucosa 250–500 mcg daily subcutaneous or oral Lyophilized: −20°C; Reconstituted: 2–8°C, use within 28 days Best-studied for soft tissue injuries. Strong pre

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  • BPC-157
  • VEGF upregulation, angiogenesis promotion, fibroblast activation
  • Tendons, ligaments, muscle, GI mucosa
  • 250–500 mcg daily subcutaneous or oral
  • Lyophilized: −20°C; Reconstituted: 2–8°C, use within 28 days
  • Best-studied for soft tissue injuries. Strong preclinical data, limited human trials
  • TB-500 (Thymosin Beta-4)
  • Actin polymerization, satellite cell migration, anti-inflammatory signaling
  • Muscle tissue, tendons, cardiac tissue post-injury
  • 2–5 mg twice weekly subcutaneous
  • Effective for muscle strain and delayed-onset soreness. Commonly used in equine research
  • PTH 1-34 (Teriparatide)
  • Osteoblast stimulation, cAMP signaling, bone matrix synthesis
  • Bone (fractures, stress fractures, osteoporotic bone)
  • 20 mcg daily subcutaneous (FDA-approved therapeutic dose)
  • Pre-filled pens: 2–8°C; Discard after 28 days
  • FDA-approved for osteoporosis. Demonstrated fracture healing benefit in clinical studies
  • GHK-Cu (Copper Peptide)
  • Collagen synthesis, antioxidant activity, MMP modulation
  • Skin, connective tissue, wound beds
  • 1–3 mg topical or subcutaneous
  • Lyophilized: −20°C; Reconstituted: 2–8°C, use within 21 days
  • Primarily wound healing and dermal repair. Weaker evidence for deep tissue injuries
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