Source comparison
PT-141 Before and After: Timeline and Dose Response Comparison
0.5mg 60–90 min 4–6 hours 15–20% +0.1–0.2 points Subtherapeutic for most. Reduces side effects but often below threshold for arousal effect 1.0mg 45–75 min 6–8 hours 25–30% +0.2–0.4 points Effective for mild HSDD. Balances efficacy and tolerability 1.75mg (FDA
This comparison does not assign a generated winner or score.
- 0.5mg
- 60–90 min
- 4–6 hours
- 15–20%
- +0.1–0.2 points
- Subtherapeutic for most. Reduces side effects but often below threshold for arousal effect
- 1.0mg
- 45–75 min
- 6–8 hours
- 25–30%
- +0.2–0.4 points
- Effective for mild HSDD. Balances efficacy and tolerability
- 1.75mg (FDA dose)
- 30–60 min
- 8–12 hours
- 40–45%
- +0.3–0.5 points
- Clinical standard. Highest efficacy within acceptable nausea threshold
- 2.0mg
- 50–55%
- No additional benefit over 1.75mg. Nausea risk outweighs marginal gains