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Source comparison

PT-141 Dosage Erectile Function 2026: Comparison Table

0.5 45–55% +1.2 6% 50–70 Subtherapeutic. Insufficient MC4R activation for consistent arousal pathway stimulation 1.0 70–80% +3.1 11% 45–60 Threshold dose. Effective in MC4R-sensitive individuals but underdosed for most subjects 1.5 85–90% +4.8 18% 40–50 Optima

This comparison does not assign a generated winner or score.

  • 0.5
  • 45–55%
  • +1.2
  • 6%
  • 50–70
  • Subtherapeutic. Insufficient MC4R activation for consistent arousal pathway stimulation
  • 1.0
  • 70–80%
  • +3.1
  • 11%
  • 45–60
  • Threshold dose. Effective in MC4R-sensitive individuals but underdosed for most subjects
  • 1.5
  • 85–90%
  • +4.8
  • 18%
  • 40–50
  • Optimal dose. Maximal efficacy with acceptable tolerability; plateau of receptor saturation curve
  • 2.0
  • 92–95%
  • +5.1
  • 34%
  • 35–45
  • Marginal efficacy gain (+0.3 points) at cost of doubled nausea incidence. Not justified
  • 2.5
  • 96–98%
  • +5.2
  • 52%
  • 30–40
  • Excessive. Adverse events outweigh negligible efficacy improvement; receptor occupancy ceiling reached
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