Source comparison
Semax Amidate vs Standard Semax: Protocol Comparison
Active Dose Range 300-600 mcg/day 600-1200 mcg/day Amidate requires half the dose for equivalent BDNF upregulation due to acetyl group stability Stability After Reconstitution 28 days refrigerated (bacteriostatic water) 14-21 days refrigerated Acetylation exte
This comparison does not assign a generated winner or score.
- Active Dose Range
- 300-600 mcg/day
- 600-1200 mcg/day
- Amidate requires half the dose for equivalent BDNF upregulation due to acetyl group stability
- Stability After Reconstitution
- 28 days refrigerated (bacteriostatic water)
- 14-21 days refrigerated
- Acetylation extends peptide half-life in solution by reducing enzymatic degradation
- Primary Mechanism
- BDNF upregulation, NGF synthesis, GABAergic modulation
- BDNF upregulation, ACTH-like effects
- Amidate targets memory-specific pathways with less pronounced stress response modulation
- Onset of Cognitive Effects
- 4-6 hours (BDNF peak)
- 2-4 hours (catecholamine response precedes BDNF)
- Standard Semax produces faster subjective alertness; Amidate produces delayed but sustained memory enhancement
- Recommended Protocol Length
- 14-30 days
- 10-21 days
- Amidate's stability supports longer cycles without potency loss
- Cost per Protocol (typical)
- $85-120 for 30-day supply at 600 mcg/day
- $60-90 for 21-day supply at 900 mcg/day
- Amidate costs more per vial but requires lower total peptide mass