Source comparison
Sermorelin Anti-Aging Protocol Dosage Timing: Type Comparison
Standard nightly 200–300 mcg 15–30 min pre-sleep 5 days on / 2 off weekly 250–300 ng/mL Baseline protocol for most researchers. Reliable GH pulse amplification without receptor saturation High-dose pulsatile 400–500 mcg 20–30 min pre-sleep 3 days on / 4 off we
This comparison does not assign a generated winner or score.
- Standard nightly
- 200–300 mcg
- 15–30 min pre-sleep
- 5 days on / 2 off weekly
- 250–300 ng/mL
- Baseline protocol for most researchers. Reliable GH pulse amplification without receptor saturation
- High-dose pulsatile
- 400–500 mcg
- 20–30 min pre-sleep
- 3 days on / 4 off weekly
- 300–350 ng/mL
- Higher peak GH but increased tachyphylaxis risk. Reserve for experienced users
- Low-dose continuous
- 150–200 mcg
- 15–25 min pre-sleep
- Daily for 16 weeks, then 4-week break
- 220–270 ng/mL
- Minimizes desensitization but slower IGF-1 elevation. Ideal for long-term maintenance
- Biphasic cycling
- 300 mcg weeks 1–6, 200 mcg weeks 7–12
- 12 weeks on / 4 weeks off
- 250–320 ng/mL
- Front-loads GH response then transitions to maintenance. Balances efficacy and receptor preservation