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Sermorelin Before and After Real Results: Comparison

IGF-1 Levels (ng/mL) 120–160 (age 40–50 avg) 150–200 160–220 Restoration to upper-normal range; sustained elevation confirms pituitary responsiveness Visceral Fat (DEXA %) 18–22% (typical adult) 16–20% 15–18% Modest but meaningful reduction; requires caloric d

This comparison does not assign a generated winner or score.

  • IGF-1 Levels (ng/mL)
  • 120–160 (age 40–50 avg)
  • 150–200
  • 160–220
  • Restoration to upper-normal range; sustained elevation confirms pituitary responsiveness
  • Visceral Fat (DEXA %)
  • 18–22% (typical adult)
  • 16–20%
  • 15–18%
  • Modest but meaningful reduction; requires caloric deficit to manifest
  • Lean Mass (kg)
  • Baseline
  • +0.5–1.5 kg
  • +1.0–2.5 kg
  • Preservation during deficit more significant than absolute gains
  • Sleep Quality (SWS duration)
  • 45–60 min/night
  • 60–75 min/night
  • 65–80 min/night
  • Polysomnography-verified increase; correlates with recovery improvements
  • Recovery Time (post-training)
  • 48–72 hours (DOMS)
  • 36–48 hours
  • 24–36 hours
  • Subjective but consistent across users; enables higher training frequency
  • Skin Elasticity (dermatology scale)
  • Moderate laxity
  • Slight improvement
  • Noticeable improvement
  • Collagen synthesis marker; visible at 4+ months
  • Sermorelin's effect on body composition is dose-dependent and ceiling-limited. Dosing typically ranges from 200–500 mcg subcutaneously before sleep. Higher doses don't produce proportionally greater results. The pituitary has a finite response capacity. Clinical data from endocrinology trials show that 300 mcg administered 5–7 days per week produces near-maximal IGF-1 elevation in most adults. Exceeding this provides diminishing returns and increases the risk of hypothalamic-pituitary axis desensitization over time.
More references

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