Source comparison
Sermorelin Body Composition Results Timeline: Clinical vs Real-World Comparison
Week 0–4 IGF-1 rises 30–50% from baseline; no measurable body composition changes on DEXA Subjective sleep quality improves; some report increased energy; no visible physique changes Dosing consistency, injection timing (pre-sleep optimal), baseline IGF-1 stat
This comparison does not assign a generated winner or score.
- Week 0–4
- IGF-1 rises 30–50% from baseline; no measurable body composition changes on DEXA
- Subjective sleep quality improves; some report increased energy; no visible physique changes
- Dosing consistency, injection timing (pre-sleep optimal), baseline IGF-1 status
- Hormonal shifts occur before structural changes. Patience is non-negotiable at this stage
- Week 8–12
- Lean mass +0.5–1.5kg, fat mass −0.5–1kg on average; strength gains in compound lifts appear
- Highly variable. Compliant users see modest visible changes; inconsistent dosing shows minimal effect
- Training stimulus, protein intake (1.6–2.2g/kg), sleep quality, caloric balance
- This is the first checkpoint where measurable results should appear; absence of change signals dosing or lifestyle issues
- Month 3–6
- Lean mass +1.5–3kg, visceral fat −2–4kg; waist circumference reduction 2–5cm
- Best results in users combining resistance training 3–4x/week with adequate recovery
- Age, training experience, genetic GH responsiveness, concurrent medications
- Peak recomposition window. After month 6, gains slow significantly even with continued dosing
- Month 6+
- Effects plateau; further gains require dose adjustment or cycling protocols
- Many users report maintenance of gains rather than continued progression
- Receptor sensitivity, natural body composition ceiling, lifestyle adherence
- Long-term use should focus on maintaining achieved composition rather than expecting continuous improvement