Source comparison
Sermorelin vs Sermorelin Acetate: Comparison
This table clarifies the functional equivalence and highlights what actually differentiates quality peptide products. Chemical Identity 29-amino-acid GHRH analogue (residues 1–29 of native GHRH) Identical peptide sequence with acetate counterion (CH₃COO⁻) bond
This comparison does not assign a generated winner or score.
- This table clarifies the functional equivalence and highlights what actually differentiates quality peptide products.
- Chemical Identity
- 29-amino-acid GHRH analogue (residues 1–29 of native GHRH)
- Identical peptide sequence with acetate counterion (CH₃COO⁻) bonded ionically
- Functionally identical. 'sermorelin' is shorthand for sermorelin acetate in all commercial contexts
- Stability in Powder Form
- Highly unstable. Absorbs moisture, aggregates rapidly, degrades within weeks at room temperature
- Stable when lyophilised. Retains potency for 24+ months at −20°C, 6–12 months at 2–8°C
- The acetate salt is why lyophilised peptides remain viable during storage and shipping
- Solubility in Bacteriostatic Water
- Poor. Base peptide resists dissolution, forms aggregates, produces cloudy solution
- Excellent. Dissolves within 60 seconds into clear solution at physiological pH
- Reconstitution behaviour is the most reliable quality indicator available to end users
- Molecular Weight
- ~3,213 Da (peptide chain only)
- ~3,358 Da (peptide + acetate)
- Weight difference is negligible for dosing calculations. Both figures refer to the same compound
- Typical Purity (HPLC)
- ≥98% (when acetate is unlisted, it's still present)
- ≥98–99% (acetate listed explicitly in product name)
- Purity percentage measures peptide sequence fidelity, not acetate presence. Compare COAs, not names
- Cost Differential
- None. Same synthesis process, same material cost
- None. 'sermorelin' and 'sermorelin acetate' are priced identically across suppliers
- Price variations reflect purity grade, batch size, and supplier overhead. Not the acetate designation