Source comparison
Side Effect Comparison
Both peptides carry favorable safety profiles compared to exogenous HGH. Neither causes the sustained supraphysiological GH levels that drive HGH's worst side effects (insulin resistance, joint swelling, carpal tunnel). But their risk profiles differ in ways t
This comparison does not assign a generated winner or score.
- Both peptides carry favorable safety profiles compared to exogenous HGH. Neither causes the sustained supraphysiological GH levels that drive HGH's worst side effects (insulin resistance, joint swelling, carpal tunnel). But their risk profiles differ in ways that matter for long-term use.
- Injection site reaction
- Common (redness, swelling, itching)
- Uncommon (mild)
- Headache
- Reported in 5 to 7% of trial participants
- Occasional, usually first week
- Peripheral edema
- Mild, in early weeks
- Rare
- Joint stiffness
- Occasional
- Nausea
- Uncommon
- Cortisol increase
- Prolactin increase
- Appetite increase
- Minimal (far less than GHRP-6)
- Paresthesia (tingling)
- Reported in ~5% of subjects
- IGF-1 elevation concern
- Must monitor; FDA label includes warning
- Moderate, upper-normal range