Source comparison
Stacking CJC-1295 Ipamorelin Sleep Optimization: Protocol Comparison
CJC-1295 Only 1–2mg weekly None Weekly Minimal (GH pulses occur but lack amplitude) 10–15% Insufficient for sleep optimization—GHRH alone doesn't trigger strong enough nocturnal pulses Ipamorelin Only 200–300mcg nightly Nightly Moderate (15–20 min reduction) 2
This comparison does not assign a generated winner or score.
- CJC-1295 Only
- 1–2mg weekly
- None
- Weekly
- Minimal (GH pulses occur but lack amplitude)
- 10–15%
- Insufficient for sleep optimization—GHRH alone doesn't trigger strong enough nocturnal pulses
- Ipamorelin Only
- 200–300mcg nightly
- Nightly
- Moderate (15–20 min reduction)
- 25–30%
- Better than baseline but lacks duration—GH pulses are sharp but short-lived
- CJC + Ipamorelin Stack
- CJC weekly, Ipamorelin nightly
- Significant (20–30 min reduction)
- 40–60%
- Optimal synergy—extended pulse duration + increased amplitude = measurable deep sleep improvement
- High-Dose Ipamorelin
- 500mcg+ nightly
- Variable (can worsen with receptor desensitisation)
- 20–35% initially, declines over 4–6 weeks
- Receptor downregulation negates benefits—higher doses don't improve outcomes