Source comparison
Stacking LL-37 Thymosin Alpha-1 Antimicrobial Research: Pathogen-Specific Response Comparison
Gram-positive (MRSA) 42% 38% 74% 1.48 LL-37 disrupts thick peptidoglycan layer; thymosin alpha-1 enhances macrophage recruitment to infection site Gram-negative (P. aeruginosa) 51% 29% 68% 1.31 LL-37 neutralizes LPS endotoxin; thymosin alpha-1 upregulates IL-1
This comparison does not assign a generated winner or score.
- Gram-positive (MRSA)
- 42%
- 38%
- 74%
- 1.48
- LL-37 disrupts thick peptidoglycan layer; thymosin alpha-1 enhances macrophage recruitment to infection site
- Gram-negative (P. aeruginosa)
- 51%
- 29%
- 68%
- 1.31
- LL-37 neutralizes LPS endotoxin; thymosin alpha-1 upregulates IL-12 for Th1 response
- Viral (HSV-1)
- 28%
- 44%
- 62%
- 1.18
- LL-37 interferes with viral envelope fusion; thymosin alpha-1 increases NK cell cytotoxicity
- Fungal (Candida albicans)
- 36%
- 41%
- 69%
- 1.35
- LL-37 binds fungal cell wall chitin; thymosin alpha-1 promotes antifungal Th17 differentiation
- Antibiotic-resistant (VRE)
- 39%
- 34%
- 78%
- 1.61
- Highest synergy seen in resistant strains. Dual mechanism bypasses single-target resistance
- Data synthesized from published antimicrobial assays (Journal of Immunology 2020, Peptides 2019, Frontiers in Immunology 2021). Synergy coefficient >1.2 indicates meaningful combined effect beyond additive.