Source comparison
TA-1 Same as Thymosin Alpha-1 Comparison
Amino Acid Sequence Identical 28-AA sequence Identical sequence (if verified) Identical sequence All variants share the same molecular structure when properly synthesized N-Terminal Acetylation Variable (60–98%) >95% guaranteed Often <90% without post-modifica
This comparison does not assign a generated winner or score.
- Amino Acid Sequence
- Identical 28-AA sequence
- Identical sequence (if verified)
- Identical sequence
- All variants share the same molecular structure when properly synthesized
- N-Terminal Acetylation
- Variable (60–98%)
- >95% guaranteed
- Often <90% without post-modification
- >98% by design
- Acetylation status is the critical quality variable. Verify by HPLC before use
- Endotoxin Limit
- Not specified (typical <10 EU/mg)
- <0.5 EU/mg (GMP requirement)
- Variable (often 5–15 EU/mg)
- <1 EU/mg (high-quality suppliers)
- For in vivo work, endotoxin below 1 EU/mg is essential to avoid LPS artifacts
- Purity (HPLC)
- 85–98%
- >95%
- 80–95%
- 95–99%
- SPPS-derived batches consistently deliver highest purity with lowest batch variation
- Regulatory Oversight
- None (research use only)
- FDA/EMA-equivalent approval
- None
- Only clinical-grade product has verified stability and potency data
- Typical Cost (per mg)
- $120–180
- $800–1200
- $80–140
- $150–220
- Research-grade offers cost advantage but requires independent verification of acetylation and endotoxin