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Targeted Fat Metabolism Versus Target Fat and Stubborn Fat Claims

AOD-9604 is sometimes described online as targeting fat cells or stubborn fat, but published evidence does not establish selective regional fat loss in patients. Preclinical work involved adipose tissue and lipid metabolism, while human trials mainly assessed

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  • AOD-9604 is sometimes described online as targeting fat cells or stubborn fat, but published evidence does not establish selective regional fat loss in patients. Preclinical work involved adipose tissue and lipid metabolism, while human trials mainly assessed body weight and related endpoints [1], [5]. A safer framing is “targeted fat metabolism has been hypothesized,” not “AOD-9604 targets stubborn fat.”
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