Source comparison
TB-500 40s Age Specific Protocol: Loading and Maintenance Schedule Comparison
20s–30s 2.5mg Twice weekly 4–6 weeks 2mg Optional Standard protocol. Hepatic clearance supports twice-weekly maintenance without inflammatory rebound 40s–50s 4 weeks 1–1.5mg Once weekly Required every 4 weeks Reduced loading dose compensates for 18–22% slower
This comparison does not assign a generated winner or score.
- 20s–30s
- 2.5mg
- Twice weekly
- 4–6 weeks
- 2mg
- Optional
- Standard protocol. Hepatic clearance supports twice-weekly maintenance without inflammatory rebound
- 40s–50s
- 4 weeks
- 1–1.5mg
- Once weekly
- Required every 4 weeks
- Reduced loading dose compensates for 18–22% slower hepatic clearance; once-weekly maintenance prevents peptide accumulation
- 50s+
- 1.5–2mg
- 1mg
- Further dose reduction accounts for additional metabolic slowdown and increased inflammatory rebound risk
- Hypothyroid (TSH >2.5)
- 1.5mg
- Thyroid dysfunction compounds clearance delays. Start low and titrate cautiously