Source comparison
TB-500 Flexibility Protocols: Research Comparison
4 weeks 2mg twice weekly 16mg total Fascial glide improvement, reduced adhesion formation Actin polymerization during early remodeling phase Minimum effective duration for measurable flexibility gains. Shorter protocols show inconsistent results 6 weeks 24mg t
This comparison does not assign a generated winner or score.
- 4 weeks
- 2mg twice weekly
- 16mg total
- Fascial glide improvement, reduced adhesion formation
- Actin polymerization during early remodeling phase
- Minimum effective duration for measurable flexibility gains. Shorter protocols show inconsistent results
- 6 weeks
- 24mg total
- Joint range of motion (goniometer-measured), tissue extensibility
- Organized collagen deposition during full turnover cycle
- Standard research protocol. Aligns with 21–28 day collagen remodeling window
- 8 weeks
- 2.5mg twice weekly
- 40mg total
- Permanent ROM gains post-protocol, reduced re-injury rates
- Extended remodeling phase with mechanical loading
- Used when targeting structural limitations (chronic capsular restrictions). Higher cost without proportional benefit for general flexibility
- 2mg three times weekly
- Acute flexibility (same outcome as 6-week protocol)
- Same mechanism as twice-weekly dosing
- No additional benefit vs. twice-weekly. Increased cost and injection frequency without improved outcomes