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TB-500 Flexibility Results Timeline Expect: Comparison

Week 1–2 No measurable change in range of motion Actin sequestration begins; collagen turnover not yet detectable Biochemical activity present but not functionally measurable. Continue protocol Week 3–4 5–12% improvement in passive joint extension MMP upregula

This comparison does not assign a generated winner or score.

  • Week 1–2
  • No measurable change in range of motion
  • Actin sequestration begins; collagen turnover not yet detectable
  • Biochemical activity present but not functionally measurable. Continue protocol
  • Week 3–4
  • 5–12% improvement in passive joint extension
  • MMP upregulation; initial scar tissue degradation
  • First objective gains appear. Validate with goniometer measurements
  • Week 5–8
  • 18–25% cumulative improvement from baseline
  • Peak collagen remodeling; organized fiber deposition
  • Optimal therapeutic window. Gains accelerate significantly
  • Week 9–12
  • 28–35% total improvement; gains plateau
  • Collagen remodeling reaches equilibrium
  • Maximum effect achieved. Further dosing maintains but doesn't increase
  • Post-Week 12
  • Gains persist if tissue maintained through movement
  • Remodeling complete; no additional peptide-driven change
  • Maintenance dose optional; flexibility improvements are structurally locked
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