Source comparison
TB-500 Hair Loss Research Comparison
Seoul National University (2019) C57BL/6 mice 2mg/kg, 3× weekly Subcutaneous injection Follicle count, anagen duration 41% increase in follicle density, 22-day anagen extension Strong preclinical signal. Demonstrates mechanism but human translation unproven Is
This comparison does not assign a generated winner or score.
- Seoul National University (2019)
- C57BL/6 mice
- 2mg/kg, 3× weekly
- Subcutaneous injection
- Follicle count, anagen duration
- 41% increase in follicle density, 22-day anagen extension
- Strong preclinical signal. Demonstrates mechanism but human translation unproven
- Istanbul University (2021)
- 18 men, Norwood III–V
- 0.5mg/mL topical
- Microneedling + topical
- Hair density via phototrichogram
- 12% density increase vs 4% microneedling alone
- Modest improvement. Below clinically transformative threshold but supports adjunct use
- In-vitro dermal papilla culture (2020)
- Human follicle cells
- 0.1–1.0 µg/mL
- Cell culture media
- Cell proliferation rate
- 34% increase in dermal papilla proliferation at 1.0 µg/mL
- Confirms cellular mechanism but dosing not directly scalable to human protocols