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Source comparison

TB-500 Joint Pain Protocol: Dosage & Timing Comparison

Acute Loading (0–4 weeks post-injury) 2–5mg Twice weekly 4 weeks VEGF upregulation, fibroblast migration, early angiogenesis Highest efficacy window. Captures inflammation-to-proliferation transition when tissue fate is determined Maintenance (4–8 weeks post-i

This comparison does not assign a generated winner or score.

  • Acute Loading (0–4 weeks post-injury)
  • 2–5mg
  • Twice weekly
  • 4 weeks
  • VEGF upregulation, fibroblast migration, early angiogenesis
  • Highest efficacy window. Captures inflammation-to-proliferation transition when tissue fate is determined
  • Maintenance (4–8 weeks post-injury)
  • 2mg
  • Once weekly
  • 4–6 weeks
  • Sustained collagen remodelling, capillary stabilisation
  • Prevents regression. Necessary to consolidate gains from loading phase
  • Chronic Pain Reactivation
  • Once weekly during flares
  • 6–12 weeks
  • Selective cytokine modulation, adhesion breakdown
  • Effective for episodic flares but limited for advanced fibrosis
  • Post-Surgical Recovery
  • 2–4mg
  • 6 weeks
  • Accelerated wound closure, reduced scar formation
  • Timing relative to surgery matters. Start within 48 hours for maximum benefit
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