TB-500 Joint Pain Protocol: Dosage & Timing Comparison
Acute Loading (0–4 weeks post-injury) 2–5mg Twice weekly 4 weeks VEGF upregulation, fibroblast migration, early angiogenesis Highest efficacy window. Captures inflammation-to-proliferation transition when tissue fate is determined Maintenance (4–8 weeks post-i
This comparison does not assign a generated winner or score.
- Acute Loading (0–4 weeks post-injury)
- 2–5mg
- Twice weekly
- 4 weeks
- VEGF upregulation, fibroblast migration, early angiogenesis
- Highest efficacy window. Captures inflammation-to-proliferation transition when tissue fate is determined
- Maintenance (4–8 weeks post-injury)
- 2mg
- Once weekly
- 4–6 weeks
- Sustained collagen remodelling, capillary stabilisation
- Prevents regression. Necessary to consolidate gains from loading phase
- Chronic Pain Reactivation
- Once weekly during flares
- 6–12 weeks
- Selective cytokine modulation, adhesion breakdown
- Effective for episodic flares but limited for advanced fibrosis
- Post-Surgical Recovery
- 2–4mg
- 6 weeks
- Accelerated wound closure, reduced scar formation
- Timing relative to surgery matters. Start within 48 hours for maximum benefit