Source comparison
TB-500 vs BPC-157 vs Growth Hormone: Comparison Table
TB-500 Actin sequestration, angiogenesis upregulation, reduces fibrosis during healing Systemic. Accumulates in areas of inflammation but circulates throughout body 2-10mg per week subcutaneous, loading phase 4-6 weeks 2.5 hours plasma, 4-7 days tissue retenti
This comparison does not assign a generated winner or score.
- TB-500
- Actin sequestration, angiogenesis upregulation, reduces fibrosis during healing
- Systemic. Accumulates in areas of inflammation but circulates throughout body
- 2-10mg per week subcutaneous, loading phase 4-6 weeks
- 2.5 hours plasma, 4-7 days tissue retention
- Best for systemic recovery, chronic tendinopathy, and injuries requiring new blood vessel formation. Slower onset but broader effect than BPC-157
- BPC-157
- Promotes fibroblast migration, stabilises gastric mucosa, modulates nitric oxide pathways
- Both systemic and localised. Can be injected near injury site for concentrated effect
- 250-500mcg daily subcutaneous or intramuscular, continuous dosing
- Unknown (peptide not fully characterised in humans)
- Faster subjective pain relief than TB-500, particularly effective for gut-related inflammation and localised soft-tissue injuries. Less evidence for structural tendon repair
- Growth Hormone (rhGH)
- Stimulates IGF-1 production in liver, direct anabolic signaling in muscle and connective tissue
- Systemic. Affects all tissues with GH receptors, not injury-specific
- 2-4 IU daily subcutaneous (therapeutic doses far exceed research use)
- 20-30 minutes plasma, IGF-1 elevation lasts 18-24 hours
- Requires sustained elevation to affect tissue repair. Expensive, requires daily dosing, risk of insulin resistance and edema at doses needed for recovery benefit
- Collagen Peptides (oral)
- Provides hydroxyproline and glycine substrate for collagen synthesis
- Absorbed systemically, no targeted delivery to injury sites
- 15-20g daily oral, taken with vitamin C
- Absorbed within 2-3 hours, incorporated into tissue over weeks
- Supports baseline collagen turnover but does not accelerate healing beyond what adequate protein intake provides. Useful as foundational support, not acute intervention