Source comparison
Tesamorelin + Ipamorelin Blend: Dosing Comparison
Tesamorelin 1mg (1mL) Once daily 30 min pre-breakfast, fasted 1mg:1mL with bacteriostatic water 7–10 days (use within this window) Primary GHRH agonist. Short half-life requires daily dosing; prepare fresh weekly Ipamorelin 200–300mcg (0.2–0.3mL) Twice daily M
This comparison does not assign a generated winner or score.
- Tesamorelin
- 1mg (1mL)
- Once daily
- 30 min pre-breakfast, fasted
- 1mg:1mL with bacteriostatic water
- 7–10 days (use within this window)
- Primary GHRH agonist. Short half-life requires daily dosing; prepare fresh weekly
- Ipamorelin
- 200–300mcg (0.2–0.3mL)
- Twice daily
- Morning (concurrent with tesamorelin) + immediately before bed, fasted
- 28 days
- Ghrelin mimetic. Stable in solution; bedtime dose critical for overnight GH surge
- Blended Protocols
- Combined as above
- Staggered (AM + PM for ipamorelin)
- Must avoid insulin spikes (≥2 hrs post-meal)
- Separate vials. Never pre-mix
- Follow shortest stability window (tesamorelin = 7–10 days)
- Synergistic when timed correctly; overlapping doses at same timepoint reduce efficacy due to receptor saturation