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Tesamorelin + Ipamorelin Blend: Protocol Comparison

Weeks 1–4 (Titration) 1mg Tesamorelin + 200mcg Ipamorelin daily Fasted state, within 30min of waking, 90min pre-meal Minimal (tolerance phase) Injection site tolerance, transient water retention Establishes baseline tolerance. Visceral fat reduction not expect

This comparison does not assign a generated winner or score.

  • Weeks 1–4 (Titration)
  • 1mg Tesamorelin + 200mcg Ipamorelin daily
  • Fasted state, within 30min of waking, 90min pre-meal
  • Minimal (tolerance phase)
  • Injection site tolerance, transient water retention
  • Establishes baseline tolerance. Visceral fat reduction not expected during this phase
  • Weeks 5–12 (Active Reduction)
  • 2mg Tesamorelin + 300mcg Ipamorelin daily
  • Same fasted-state protocol
  • 8–15% VAT volume reduction
  • Waist circumference (−2 to −5cm), fasting glucose improvement
  • Primary treatment window. Most measurable visceral adipose loss occurs here
  • Weeks 13–26 (Maintenance)
  • 2mg Tesamorelin + 300mcg Ipamorelin 5 days/week
  • Sustained reduction, minimal further loss
  • Stable waist circumference, metabolic markers
  • Prevents VAT rebound. Full daily dosing can be reduced to 5x/week without reversal
  • Post-Protocol (Discontinuation)
  • None
  • N/A
  • VAT regain of 40–60% within 12 weeks if discontinued
  • Gradual waist circumference increase
  • Peptide-driven VAT reduction reverses without continued GH stimulus. This is a biological reality, not protocol failure
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