Tesamorelin + Ipamorelin Blend: Real vs Fake Comparison
This table contrasts verified authentic blends with common counterfeit or degraded substitutes across the three most critical verification dimensions. HPLC Purity Report ≥98% purity for each peptide separately, with batch-specific chromatograms showing single
This comparison does not assign a generated winner or score.
- This table contrasts verified authentic blends with common counterfeit or degraded substitutes across the three most critical verification dimensions.
- HPLC Purity Report
- ≥98% purity for each peptide separately, with batch-specific chromatograms showing single dominant peaks at expected retention times
- Generic CoA showing 'total peptide content' without individual peptide separation, or purity <95% with multiple unidentified peaks
- HPLC is non-negotiable. A blend CoA must report both peptides independently with retention time data
- Mass Spectrometry Confirmation
- Molecular weight confirmed at 5,136 Da for tesamorelin and 711.85 Da for ipamorelin via MS or MALDI-TOF
- No MS data provided, or molecular weights that deviate by >2 Da from expected values
- MS is the only method that confirms amino acid sequence accuracy. HPLC alone can't distinguish substituted analogs
- Endotoxin Testing
- <5 EU/mg documented via LAL (limulus ameboid lysate) assay with test date and method reference
- No endotoxin data on CoA, or results showing >10 EU/mg
- Endotoxin contamination triggers inflammatory confounds in research. Untested peptides are scientifically unreliable
- Reconstitution Behavior
- Complete dissolution in bacteriostatic water within 60–90 seconds, no cloudiness or particulates
- Persistent cloudiness, incomplete dissolution after 5+ minutes, or visible particulates settling at vial bottom
- Reconstitution failure is the earliest physical signal of degraded or substituted peptide. Often visible before biological testing
- Supplier Transparency
- Provides batch-specific CoAs with accredited lab signatures (e.g., ISO 17025), cold-chain shipping documentation, and retest dates
- Generic CoAs with no batch numbers, test dates >6 months old, or no third-party lab accreditation listed
- Third-party verification removes conflict of interest. In-house testing by the supplier isn't independent confirmation