Source comparison
Tesamorelin + Ipamorelin Blend: Research Models Comparison
Age-related GH decline Peak GH amplitude restoration Moderate (1.8× baseline) Minimal (1.2× baseline) High (3.1× baseline) Blend replicates youthful pulsatile secretion. Essential for aging models Visceral adipose reduction % reduction in VAT mass 9% at 12 wee
This comparison does not assign a generated winner or score.
- Age-related GH decline
- Peak GH amplitude restoration
- Moderate (1.8× baseline)
- Minimal (1.2× baseline)
- High (3.1× baseline)
- Blend replicates youthful pulsatile secretion. Essential for aging models
- Visceral adipose reduction
- % reduction in VAT mass
- 9% at 12 weeks
- 6% at 12 weeks
- 18% at 12 weeks
- Synergistic lipolysis effect not seen with monotherapy
- Lean mass preservation
- Change in lean tissue mass
- +3%
- +2%
- +7%
- Dual IGF-1 upregulation plus protein synthesis signalling
- Insulin sensitivity
- HOMA-IR score change
- No significant change
- Slight improvement
- Moderate improvement (−22%)
- Pulsatile GH preserves insulin sensitivity vs continuous elevation
- GH pulse duration
- Hours of elevated plasma GH
- 1.5–2 hours
- 1–1.5 hours
- 4–6 hours
- Extended secretory window allows downstream metabolic effects to manifest