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Tesamorelin + Ipamorelin: Blood Work Comparison

Serum IGF-1 80–150 ng/mL (age-dependent) 150–280 ng/mL (+50–150 from baseline) Primary endpoint. Confirms pituitary GH response Fasting Glucose 70–99 mg/dL Stable or reduced (<90 mg/dL) Rising glucose suggests excessive dose or insulin resistance Fasting Insul

This comparison does not assign a generated winner or score.

  • Serum IGF-1
  • 80–150 ng/mL (age-dependent)
  • 150–280 ng/mL (+50–150 from baseline)
  • Primary endpoint. Confirms pituitary GH response
  • Fasting Glucose
  • 70–99 mg/dL
  • Stable or reduced (<90 mg/dL)
  • Rising glucose suggests excessive dose or insulin resistance
  • Fasting Insulin
  • 2–12 µIU/mL
  • Reduced (<10 µIU/mL)
  • Elevated insulin (>15) = dose too high for metabolic state
  • Triglycerides
  • 50–200 mg/dL
  • Reduced 20–40% from baseline
  • Confirms adipose mobilization. Absent change = non-response
  • HDL Cholesterol
  • 40–60 mg/dL
  • Elevated 5–10 mg/dL
  • GH-mediated lipolysis raises HDL; unchanged HDL = underdosing
  • AST/ALT (Liver Enzymes)
  • <40 U/L
  • Transient rise <1.5× ULN acceptable
  • Elevations >1.5× ULN require dose reduction
  • Hemoglobin A1c
  • 4.5–5.6%
  • Stable or reduced (<5.4%)
  • Rising A1c despite normal fasting glucose = impaired postprandial control
  • Professional Assessment
  • Establish numeric baseline for dose titration
  • Dose-response confirmed if IGF-1 rises 50+ ng/mL with stable glucose and reduced triglycerides
  • Labs guide continuation, dose adjustment, or discontinuation. Subjective assessment alone misses metabolic dysfunction
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