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Tesamorelin vs HGH

Tesamorelin and recombinant human growth hormone (HGH) both increase GH and IGF-1 levels, but they do so through fundamentally different mechanisms that produce meaningfully different risk profiles. Tesamorelin stimulates the pituitary to release GH in natural

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  • Tesamorelin and recombinant human growth hormone (HGH) both increase GH and IGF-1 levels, but they do so through fundamentally different mechanisms that produce meaningfully different risk profiles. Tesamorelin stimulates the pituitary to release GH in natural pulses; HGH bypasses the pituitary entirely and delivers a continuous bolus of exogenous hormone³.
  • This distinction plays out in three important ways:
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