Thymosin Alpha-1 Storage: Lyophilised vs Reconstituted
Lyophilised powder (unopened) −20°C preferred; −10°C to 4°C acceptable for <6 months 12–24 months at −20°C Minimal. Moisture ingress only if seal compromised Powder should be white/off-white, free-flowing; clumping indicates moisture exposure Reconstituted wit
This comparison does not assign a generated winner or score.
- Lyophilised powder (unopened)
- −20°C preferred; −10°C to 4°C acceptable for <6 months
- 12–24 months at −20°C
- Minimal. Moisture ingress only if seal compromised
- Powder should be white/off-white, free-flowing; clumping indicates moisture exposure
- Reconstituted with bacteriostatic water
- 2–8°C (refrigerated). Mandatory
- 28 days
- High if temperature exceeds 8°C for >6 hours; irreversible denaturation above 25°C
- No reliable visual markers. Clear solution even when degraded
- Reconstituted with sterile water (no preservative)
- 7–10 days
- Same thermal risk + microbial contamination risk without preservative
- Same. Clear solution does not indicate potency
- Accidental room temperature storage (20–25°C)
- N/A (storage error)
- <72 hours before significant loss
- Severe. 40% activity loss by 72 hours; complete loss by 7 days
- None. Appears normal despite degradation
- Professional Assessment
- Lyophilised peptides tolerate brief shipping delays; reconstituted solutions do not. Once mixed, refrigeration is non-negotiable. There is no 'grace period' for room temperature storage.