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Thymosin Alpha-1 vs LL-37 vs Combination Protocol: Immune Marker Comparison

CD4+ T-cell proliferation (% increase at 72hr) 35–50% 5–10% 40–55% Tα1 drives this metric; LL-37 adds minimal contribution Neutrophil chemotaxis (fold-increase) 1.2–1.5× 3.5–4.2× 4.0–4.8× LL-37 dominates; combination shows slight additive effect IL-2 productio

This comparison does not assign a generated winner or score.

  • CD4+ T-cell proliferation (% increase at 72hr)
  • 35–50%
  • 5–10%
  • 40–55%
  • Tα1 drives this metric; LL-37 adds minimal contribution
  • Neutrophil chemotaxis (fold-increase)
  • 1.2–1.5×
  • 3.5–4.2×
  • 4.0–4.8×
  • LL-37 dominates; combination shows slight additive effect
  • IL-2 production (pg/mL increase)
  • 180–220
  • 20–40
  • 200–240
  • Tα1-dependent; LL-37 contributes minor upregulation
  • Biofilm disruption (% reduction at 12hr)
  • 10–15%
  • 60–75%
  • 65–80%
  • LL-37 mechanism; Tα1 provides negligible direct effect
  • Infection clearance time (days, bacterial model)
  • 8–10
  • 6–8
  • 4.5–6
  • Synergy visible here. Combination outperforms either alone by 25–40%
  • Professional Assessment
  • Strong adaptive priming but slow pathogen clearance
  • Rapid innate response but no long-term immunity
  • Dual-axis coverage. Adaptive scaffolding + immediate pathogen reduction
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