Source comparison
Tolerance to Melanotan-1 Cycling: Protocol Comparison
Daily continuous (0.5mg) 52–58% of baseline Week 7–8, begins fading week 10 8–10 weeks before diminishing returns 56mg Fastest initial tanning but earliest tolerance onset. Requires longest washout (6+ weeks) to restore receptors Alternate-day (0.5mg, 3.5x/wee
This comparison does not assign a generated winner or score.
- Daily continuous (0.5mg)
- 52–58% of baseline
- Week 7–8, begins fading week 10
- 8–10 weeks before diminishing returns
- 56mg
- Fastest initial tanning but earliest tolerance onset. Requires longest washout (6+ weeks) to restore receptors
- Alternate-day (0.5mg, 3.5x/week)
- 68–74% of baseline
- Week 8–9, sustains through week 12
- 10–12 weeks sustained response
- 28mg
- Optimal balance. Preserves receptor density while maintaining consistent melanogenesis; half the peptide consumption of daily
- Front-loaded (1.5mg week 1, then 0.5mg daily)
- 48–54% of baseline
- Week 6–7, sharp decline after week 9
- 7–9 weeks before requiring escalation
- 60mg+
- Accelerates tolerance without proportional tanning benefit. Reaches receptor ceiling fastest
- Pulsatile (3 days on, 4 days off within cycle)
- 78–82% of baseline
- Week 9–10, maintains through week 14
- 12–14 weeks before plateau
- 24mg
- Slowest melanin accumulation initially but longest sustainable response. Best for minimising total exposure