Source comparison
What evidence supports cyclical versus continuous NAD+ use?
Oral NAD+ precursors (NMN, NR) can be taken continuously without cycling — they support an ongoing metabolic process rather than triggering a one-time repair. Injectable NAD+ is typically run in defined courses: a loading phase followed by weekly maintenance f
This comparison does not assign a generated winner or score.
- Oral NAD+ precursors (NMN, NR) can be taken continuously without cycling — they support an ongoing metabolic process rather than triggering a one-time repair. Injectable NAD+ is typically run in defined courses: a loading phase followed by weekly maintenance for 2–3 months, then reassess. Some practitioners recommend periodic IV loading courses (quarterly) with continuous oral supplementation in between. There is no evidence of tolerance buildup with oral precursors.